Yes, just plug a guitar to Inst IN jack and select one of the 10 AmpTones or the special acoustic guitar setting. They amp characteristics range from Clean to Insane distortion with user variable Drive amount. All feature editable 3 band tone, compression and speaker emulation controls.
Additionally, the Advanced Guitar FX section offers controls for simple-to-use guitar effects including Distortions, Flange, Chorus, Delay, Reverb, EQ (treble, mid, bass) and Comp.
Please note: To pass guitar signals to an amplifier and bypass internal guitar processing, connect a 1/4” cable to your guitar rig from the THRU jack.